Infant colic, or baby colic, is a common but poorly understood and often frustrating problem for parents and caregivers.
It refers to a clinical condition of inconsolable crying, fussing and irritability, most often in the evenings,in an otherwise healthy baby during the first three months of life.
Loud crying lasting three hours or more for three or more days a week, over a period of more than three weeks.
The occurence of infant colic ranges widely. As many as up to 26% of infants are diagnosed with colic, making the condition one of the most frequent reasons for visits to paediatricians, family practitioners and community nurses.
According to the Rome III diagnostic criteria for functional gastrointestinal disorders, a child has infant colic if it has unexplained episodes of paroxysmal fussing and crying for at least three hours a day for three days a week or more for at least one week.
Despite decades of research the cause of infant colic remains uncertain, but there are probably multiple contributing factors. Both the role of behavioural factors as well as biological components have been discussed.
In recent years the role of the gastrointestinal microbiota has come into focus and lower counts of intestinal lactobacilli and increased concentrations of coliform bacteria have been observed in colicky infants compared to healthy ones.
Lactobacillus-reuteri in Ezegut produces “reuterin”, which causes oxidative stress in E. coli, therefore kills the fecal gas-forming E. coli.
Post natal neuronal development & regulation of GI motility.
Down-regulates the pro-inflammatory cytokines in the intestine & decreases calprotectin levels thus, inhibits gut inflammation.
Maintains gut flora via colonization & develops acquired